Nutramigen® Ready-to-Feed & Concentrate
Hypoallergenic formula with extensively hydrolyzed protein for infants with food allergies, including cow’s milk allergy
Nutramigen is clinically shown to quickly manage colic due to cow’s milk allergy
- Starts to reduce excessive crying* in less than 24 hours.¹ A significant reduction in excessive crying* was observed in ~90% infants within 2 days¹ (see study)
- Lower eczema severity scores at 3 months² (see study)
Additional product features:
- Hypoallergenic protein source (extensively hydrolyzed casein)
- Expert-recommended DHA at 0.32% of total fatty acids, the same as the worldwide breast milk average3,4†
- Has no sucrose added as a carbohydrate source‡
- Lactose-free
- No artificial growth hormones§
*Reduced crying in ~90% of infants within 48 hours when managing colic due to cow's milk allergy. Studied before the addition of DHA, ARA, or LGG.
†The World Health Organization recommended amount of DHA is 0.2% - 0.36% of total fatty acids. Average DHA in worldwide breast milk is 0.32% ± 0.22% (mean ± standard deviation of total fatty acids) based on an analysis of 65 studies of 2,474 women.¹⁰
‡When sucrose is not preferred.
§No significant difference has been shown between milk drived from rbST-treated and non-rbST-treated cows.
Patient Savings & Support Programs Helping Hands™ Reimbursement Support
Navigating insurance coverage is not always easy. Through Helping Hands™, our team of dedicated reimbursement experts can help guide parents through the process from start to finish. From benefits verification to prior authorization assistance, we handle all the details so patients can get quick access to Mead Johnson Nutrition products when prescribed.
See more about Helping Hands™ Reimbursement Support
Savings and assistance programs for your patients
Mead Johnson offers a range of savings and assistance programs to support parents when they need it most, including Enfamil® Family Beginnings and Helping Hands™ Sample Assistance.
Learn more about patient support here
Nutramigen is designed to provide a sole source of nutrition for infants up to age 6 months, and provide a major source of nutrition through 12 months of age. Normally, in feeding infants, gradual introduction of solid foods after 4–6 months of age is an important developmental as well as nutritional step.
In cases of severe and multiple food allergies or intolerances, Nutramigen is sometimes continued in the diet of children.
Extended use of Nutramigen as a sole source of nutrition should be used with medical supervision.
Ingredients: Ready to Feed (2 fl oz Nursette® bottle): Water (87%), corn syrup solids (5%), vegetable oil (palm olein, soy, coconut and high oleic sunflower oils) (3%), casein hydrolysate* (milk) (2%), modified corn starch (2%) and less than 1%: Mortierella alpina oil†, Schizochytrium sp. oil‡, carrageenan, vitamin A palmitate, vitamin D3, vitamin E acetate, vitamin K1, thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, vitamin B12, niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid, choline chloride, inositol, calcium carbonate, calcium phosphate, magnesium oxide, ferrous sulfate, zinc sulfate, manganese sulfate, cupric sulfate, sodium iodide, sodium selenite, sodium citrate, potassium citrate, potassium chloride, citric acid, taurine, L-cystine, L-tyrosine, L-tryptophan, L-carnitine.
Ingredients: Ready To Feed (6 fl oz bottle): Water (87%), corn syrup solids (5%), vegetable oil (palm olein, coconut, soy and high oleic sunflower oils) (4%), casein hydrolysate* (milk) (2%), modified corn starch (2%) and less than 1%: Mortierella alpina oil†, Schizochytrium sp. oil‡, calcium phosphate, potassium citrate, calcium carbonate, potassium chloride, sodium citrate, magnesium oxide, ferrous sulfate, zinc sulfate, cupric sulfate, manganese sulfate, sodium iodide, sodium selenite, carrageenan, choline chloride, ascorbic acid, vitamin E acetate, niacinamide, calcium pantothenate, vitamin A palmitate, thiamin hydrochloride, riboflavin, vitamin D3, vitamin B6 hydrochloride, folic acid, vitamin K1, biotin, L-cystine, inositol, L-tyrosine, L-tryptophan, vitamin B12, taurine, L-carnitine.
Ingredients: Ready To Feed (8 fl oz bottle): Water (87%), corn syrup solids (5%), vegetable oil (palm olein, coconut, soy and high oleic sunflower oils) (3%), casein hydrolysate* (milk) (2%), modified corn starch (2%) and less than 1%: Mortierella alpina oil†, Schizochytrium sp. oil‡, calcium phosphate, potassium citrate, calcium carbonate, potassium chloride, sodium citrate, magnesium oxide, ferrous sulfate, zinc sulfate, cupric sulfate, manganese sulfate, sodium iodide, sodium selenite, carrageenan, citric acid, choline chloride, ascorbic acid, vitamin E acetate, niacinamide, calcium pantothenate, vitamin A palmitate, thiamin hydrochloride, riboflavin, vitamin D3, vitamin B6 hydrochloride, folic acid, vitamin K1, biotin, L-cystine, inositol, L-tyrosine, L-tryptophan, vitamin B12, taurine, L-carnitine.
Ingredients: Ready To Feed (32 fl oz bottle): Water (87%), corn syrup solids (5%), vegetable oil (palm olein, soy, coconut, and high oleic sunflower oils) (4%), casein hydrolysate* (milk) (2%), modified corn starch (2%) and less than 1%: Mortierella alpina oil†, Schizochytrium sp. oil‡, carrageenan, vitamin A palmitate, vitamin D3, vitamin E acetate, vitamin K1, thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, vitamin B12, niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid, choline chloride, inositol, calcium carbonate, calcium phosphate, magnesium oxide, ferrous sulfate, zinc sulfate, manganese sulfate, cupric sulfate, potassium iodide, sodium selenite, sodium citrate, potassium citrate, potassium chloride, citric acid, taurine, L-cystine, L-tyrosine, L-tryptophan, L-carnitine.
Ingredients: Concentrate (13 fl oz can): Water (75%), corn syrup solids (10%), vegetable oil (palm olein, soy, coconut and high oleic sunflower oils) (7%), casein hydrolysate* (milk) (4%), modified corn starch (3%) and less than 1%: Mortierella alpina oil†, Schizochytrium sp. oil‡, acetylated monoglycerides, carrageenan, vitamin A palmitate, vitamin D3, vitamin E acetate, vitamin K1, thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, vitamin B12, niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid, choline chloride, inositol, calcium carbonate, calcium phosphate, magnesium oxide, ferrous sulfate, zinc sulfate, manganese sulfate, cupric sulfate, sodium iodide, sodium selenite, sodium citrate, potassium citrate, potassium chloride, citric acid, taurine, L-cystine, L-tyrosine, L-tryptophan, L-carnitine.
*Modified to be better tolerated in milk-allergic babies.
†A source of arachidonic acid (ARA).
‡A source of docosahexaenoic acid (DHA).
ALLERGEN INFORMATION
Nutramigen® contains milk. Nutramigen is hypoallergenic. Allergic reactions to extensively hydrolyzed casein formulas are not commonly reported.
Ingredient Transparency
Explore the function behind our ingredients.
| (Normal Dilution) | Per 100 Cal 2 fl oz RTU | Per 100 Cal 6 fl oz RTU | Per 100 Cal 8 fl oz RTU | Per 100 Cal 13 fl oz Conc | Per 100 Cal 32 fl oz RTU | Per 100 mL 2 fl oz RTU | Per 100 mL 6 fl oz RTU | Per 100 mL 8 fl oz RTU | Per 100 mL 13 fl oz Conc | Per 100 mL 32 fl oz RTU |
|---|---|---|---|---|---|---|---|---|---|---|
| Protein, g | 2.8 | 2.8 | 2.8 | 2.8 | 2.8 | 1.89 | 1.89 | 1.89 | 1.89 | 1.89 |
| Fat, g | 5.3 | 5.3 | 5.3 | 5.3 | 5.3 | 3.6 | 3.6 | 3.6 | 3.6 | 3.6 |
| Linoleic acid, mg | 780 | 780 | 780 | 780 | 780 | 530 | 530 | 530 | 530 | 530 |
| Carbohydrate, g | 10.3 | 10.3 | 10.3 | 10.3 | 10.3 | 7 | 7 | 7 | 7 | 7 |
| Water, g | 132 | 132 | 132 | 133 | 132 | 89 | 89 | 89 | 90 | 89 |
| Vitamins/Other Nutrients | ||||||||||
| Vitamin A, IU | 300 | 300 | 300 | 300 | 300 | 200 | 200 | 200 | 200 | 200 |
| Vitamin D, IU | 45 | 50 | 50 | 50 | 50 | 30 | 34 | 34 | 34 | 34 |
| Vitamin E, IU | 2 | 2 | 2 | 2 | 2 | 1.35 | 1.35 | 1.35 | 1.35 | 1.35 |
| Vitamin K, mcg | 9 | 9 | 9 | 9 | 9 | 6.1 | 6.1 | 6.1 | 6.1 | 6.1 |
| Thiamin (Vitamin B1), mcg | 80 | 80 | 80 | 80 | 80 | 54 | 54 | 54 | 54 | 54 |
| Riboflavin (Vitamin B2), mcg | 90 | 90 | 90 | 90 | 90 | 61 | 61 | 61 | 61 | 61 |
| Vitamin B6, mcg | 60 | 60 | 60 | 60 | 60 | 41 | 41 | 41 | 41 | 41 |
| Vitamin B12, mcg | 0.3 | 0.3 | 0.3 | 0.3 | 0.3 | 0.2 | 0.2 | 0.2 | 0.2 | 0.2 |
| Niacin, mcg | 1000 | 1000 | 1000 | 1000 | 1000 | 680 | 680 | 680 | 680 | 680 |
| Folic acid (Folacin), mcg | 16 | 16 | 16 | 16 | 16 | 10.8 | 10.8 | 10.8 | 10.8 | 10.8 |
| Pantothenic acid, mcg | 500 | 500 | 500 | 500 | 500 | 340 | 340 | 340 | 340 | 340 |
| Biotin, mcg | 3 | 3 | 3 | 3 | 3 | 2 | 2 | 2 | 2 | 2 |
| Vitamin C (Ascorbic acid), mg | 12 | 12 | 12 | 12 | 12 | 8.1 | 8.1 | 8.1 | 8.1 | 8.1 |
| Choline, mg | 24 | 24 | 24 | 24 | 24 | 16.2 | 16.2 | 16.2 | 16.2 | 16.2 |
| Inositol, mg | 24 | 24 | 24 | 24 | 24 | 16.2 | 16.2 | 16.2 | 16.2 | 16.2 |
| Minerals | ||||||||||
| Calcium, mg | 94 | 94 | 94 | 94 | 94 | 64 | 64 | 64 | 64 | 64 |
| Phosphorus, mg | 52 | 52 | 52 | 52 | 52 | 35 | 35 | 35 | 35 | 35 |
| Magnesium, mg | 8 | 8 | 8 | 8 | 8 | 5.4 | 5.4 | 5.4 | 5.4 | 5.4 |
| Iron, mg | 1.8 | 1.8 | 1.8 | 1.8 | 1.8 | 1.22 | 1.22 | 1.22 | 1.22 | 1.22 |
| Zinc, mg | 1 | 1 | 1 | 1 | 1 | 0.68 | 0.68 | 0.68 | 0.68 | 0.68 |
| Manganese, mcg | 25 | 25 | 25 | 25 | 25 | 16.9 | 16.9 | 16.9 | 16.9 | 16.9 |
| Copper, mcg | 75 | 75 | 75 | 75 | 75 | 51 | 51 | 51 | 51 | 51 |
| Iodine, mcg | 15 | 15 | 15 | 15 | 15 | 10.1 | 10.1 | 10.1 | 10.1 | 10.1 |
| Selenium, mcg | 2.8 | 2.8 | 2.8 | 2.8 | 2.8 | 1.89 | 1.89 | 1.89 | 1.89 | 1.89 |
| Sodium, mg | 47 | 47 | 47 | 47 | 47 | 32 | 32 | 32 | 32 | 32 |
| Potassium, mg | 110 | 110 | 110 | 110 | 110 | 74 | 74 | 74 | 74 | 74 |
| Chloride, mg | 86 | 86 | 86 | 86 | 86 | 58 | 58 | 58 | 58 | 58 |
Product nutrient values and ingredients are subject to change. Please see product label for current information
| Nutrient Density | 20 Cal/fl oz 2 & 6 fl oz | 20 Cal/fl oz 13 fl oz | 20 Cal/fl oz 8 & 32 fl oz |
|---|---|---|---|
| RTF | Concentrate | RTF | |
| Protein (% Calories) | 11 | 11 | 11 |
| Fat (% Calories) | 48 | 48 | 48 |
| Carbohydrate (% Calories) | 41 | 41 | 41 |
| Potential Renal Solute Load (mOsm/100 Calories)1 | 25 | 25 | 25 |
| Potential Renal Solute Load (mOsm/100 mL)1 | 16.9 | 16.9 | 16.9 |
| Osmolality (mOsm/kg water) | 280 | 270 | 280 |
| Osmolarity (mOsm/L) | 250 | 240 | 250 |
| Lactose-Free | Yes | Yes | Yes |
AMINO ACID COMPOSITION
Essential and Nonessential Amino Acids
DILUTION INFORMATION FOR NUTRAMIGEN LIQUIDS
Dilution instructions for concentrated liquid formula
Download dilution information per 13 fl oz can ↗
CONCENTRATE
A baby’s health depends on carefully following the instructions below. Use only as directed by a medical professional. Proper hygiene, preparation, dilution, use and storage are important when preparing infant formula. Discuss with parents which formula is appropriate for the baby, the need to use cooled, boiled water for mixing and the need to boil clean utensils, bottles and nipples in water before use.
13 fl oz Cans
- Wash hands thoroughly with soap and water before preparing formula.
- Clean can lid, SHAKE CAN WELL and open.
- Pour desired amount of water into the bottle. Add an equal amount of concentrated liquid. Shake or stir well.
WARNING: Do not use a microwave oven to warm formula. Serious burns may result.
Failure to follow these instructions could result in severe harm. Opened cans and prepared formula can spoil quickly. Either feed immediately or cover and store in refrigerator at 35–40°F (2–4°C) for no longer than 48 hours. Do not use opened cans and/or prepared formula if they are unrefrigerated for more than a total of 2 hours. Do not freeze prepared formula. After feeding begins, use prepared formula within 1 hour or discard.
Storage: Store unopened cans at room temperature. Avoid excessive heat. Do not freeze. Nutramigen 1 does not look or taste like milk or soy formulas. It may separate in the refrigerator. Shake well before feeding.
USE BY DATE ON BOTTOM OF CAN.
NURSETTE® BOTTLES
A baby’s health depends on carefully following the instructions below. Use only as directed by a medical professional. Proper hygiene, preparation, use and storage are important when preparing infant formula. Discuss with parents which formula is appropriate for the baby and the need to boil a clean nipple in water before use.
2 & 6 fl oz Nursette Bottles
- Inspect each bottle for signs of damage.
- Wash hands thoroughly with soap and water before preparing bottle for feeding.
- SHAKE BOTTLE WELL and remove cap.
- Attach nipple unit (not included).
WARNING: Do not use a microwave oven to warm formula. Serious burns may result.
Failure to follow these instructions could result in severe harm. Opened bottles can spoil quickly. Either feed immediately or replace cap and store in refrigerator at 35–40°F (2–4°C) for no longer than 24 hours. Do not use opened bottle if it is unrefrigerated for more than a total of 2 hours. Do not freeze. After feeding begins, use formula within 1 hour or discard.
Storage: Store unopened bottle at room temperature. Avoid excessive heat and prolonged exposure to light. Do not freeze.
Nutramigen does not look or taste like milk or soy formulas. Product may separate. Shake well before feeding.
USE BY DATE ON CARTON AND BOTTLE LABEL
DO NOT USE IF CAP RING IS BROKEN OR MISSING. DO NOT ACCEPT IF PACKAGE HAS BEEN OPENED.
READY-TO-FEED
A baby’s health depends on carefully following the instructions below. Use only as directed by a medical professional. Proper hygiene, preparation, use and storage are important when preparing infant formula. Discuss with parents which formula is appropriate for the baby and the need to boil clean utensils, feeding bottles, and nipples in water before use. Inspect bottle for signs of damage.
8 fl oz Bottles
- Wash hands thoroughly with soap and water before preparing feeding bottles.
- SHAKE BOTTLE WELL, remove protective seal around cap, remove cap and foil seal. Replace cap.
- Pour into feeding bottle(s).
WARNING: Do not use a microwave oven to warm formula. Serious burns may result.
Failure to follow these instructions could result in severe harm. Opened bottles and prepared formula can spoil quickly. Either feed immediately or cover and store in refrigerator at 35–40°F (2–4°C) for no longer than 48 hours. Do not use opened bottle and/or prepared formula if they are unrefrigerated for more than a total of 2 hours. Do not freeze prepared formula. After feeding begins, use prepared formula within 1 hour or discard.
Storage: Store unopened bottle at room temperature. Avoid excessive heat. Do not freeze. This product does not look or taste like milk or soy formulas. Product may separate. Shake well before feeding.
USE BY DATE ON SIDE OF BOTTLE.
DO NOT USE IF PROTECTIVE SEAL AROUND CAP, OR IF FOIL SEAL UNDER CAP, IS DAMAGED OR MISSING.
32 fl oz Bottles
- Wash hands thoroughly with soap and water before preparing feeding bottles.
- SHAKE BOTTLE WELL, remove protective seal around cap, remove cap and foil seal. Replace cap.
- Pour into feeding bottle(s).
WARNING: Do not use a microwave oven to warm formula. Serious burns may result.
Failure to follow these instructions could result in severe harm. Opened bottles and prepared formula can spoil quickly. Either feed immediately or cover and store in refrigerator at 35–40°F (2–4°C) for no longer than 48 hours. Do not use opened bottle and/or prepared formula if they are unrefrigerated for more than a total of 2 hours. Do not freeze prepared formula. After feeding begins, use prepared formula within 1 hour or discard.
Storage: Store unopened bottle at room temperature. Avoid excessive heat. Do not freeze. Nutramigen does not look or taste like milk or soy formulas. Product may separate. Shake well before feeding.
USE BY DATE ON SIDE OF BOTTLE.
DO NOT USE IF PROTECTIVE SEAL AROUND CAP, OR IF FOIL SEAL UNDER CAP, IS DAMAGED OR MISSING.
NUTRAMIGEN IS AVAILABLE IN READY-TO-FEED LIQUID AND CONCENTRATE
Coding systems and reimbursement allowable rates vary by payer:
- Medicare Part B uses HCPCS (Healthcare Common Procedure Coding System) to group products
- Medicaid systems vary by state; some use HCPCS while others use NDC format code or systems of their own—contact your state provider for more information
- Private health insurance and managed care companies may use HCPCS, NDC format code or their own system—contact your provider for more information
Nutramigen®, Ready-to-Feed (2 fl oz Nursette® bottle)
Item #: 898301
Description: RTF
Unit Size: 2 fl oz bottle
Calories/Unit: 40
Product Yield/Unit (fl oz): 2
Case: 48 bottles per case
HCPCS Code: B4161
NDC Format Code: 00087-1437-41
Nutramigen®, Ready-to-Feed (6 fl oz bottle)
Item #: 898401
Description: RTF
Unit Size: 6 fl oz bottle
Calories/Unit: 120
Product Yield/Unit (fl oz): 6
Case: 24 bottles per case
HCPCS Code: B4161
NDC Format Code: 00087-5105-17
Nutramigen®, Ready-to-Feed (8 fl oz bottle)
Item #: 898207
Description: RTF
Unit Size: 8 fl oz bottle
Calories/Unit: 24 bottles per case
Product Yield/Unit (fl oz): 8
Case: B4161
HCPCS Code: 00087-5131-47
Nutramigen®, Ready-to-Feed (32 fl oz bottle)
Item #: 898202
Description: RTF
Unit Size: 32 fl oz bottle
Calories/Unit: 640
Product Yield/Unit (fl oz): 32
Case: 6 bottles per case
HCPCS Code: B4161
NDC Format Code: 00087-5115-64
Nutramigen®, Concentrate (13 fl oz can)
Item #: 898501
Description: Concentrate
Unit Size: 13 fl oz can
Calories/Unit: 520
Product Yield/Unit (fl oz): 26
Case: 12 cans per case
HCPCS Code: B4161
NDC Format Code: 00087-0498-01
Clinical Study
Cow's milk whey protein elicits symptoms of infantile colic in colicky formula-fed infants: a double-blind crossover study
Clinical Study
Nutramigen Letter of Medical Necessity
Letters of medical necessity are available to help make accessing the Mead Johnson formula you recommend easier for your patients. Use this form for patients prescribed Nutramigen®, Nutramigen® with Probiotic LGG®, or Nutramigen® with Probiotic LGG® Toddler.
- Lothe L, Lindberg T. Cow’s milk whey protein elicits symptoms of infantile colic in colicky formula-fed infants: a double-blind crossover study. Pediatrics. 1989;83:262-266.
- Nermes M, Kantele JM, Atosuo TJ, Salminen S, Isolauri E. Interaction of orally administered Lactobacillus rhamnosus GG with skin and gut microbiota and humoral immunity in infants with atopic dermatitis. Clin Exp Allergy. 2011;41(3):370-377.
- Hoffman DR, Birch EE, Birch DG, et al. Impact of early dietary intake and blood lipid composition of long-chain polyunsaturated fatty acids on later visual development. J Pediatr Gastroenterol Nutr. 2000;31:540-553.
- Birch EE, Castañeda YS, Wheaton DH, et al. Visual maturation of term infants fed long-chain polyunsaturated fatty acid-supplemented or control formula for 12 mo. Am J Clin Nutr. 2005;81:871-879.