Fast relief today and lasting relief through early childhood1-5*†‡
Only Nutramigen® with Probiotic LGG® has published data on significant symptom improvement & fewer allergies through 6 years1-5*
*Published studies showing fewer incidences of urticaria, eczema, asthma, and rhinoconjunctivitis in infants with IgE-mediated cow’s milk allergy through 6 years compared to hydrolyzed rice, soy, extensively hydrolyzed whey, and amino acid formulas.
†Lasting relief = reduced allergic march at 3 years and 6 years.
‡Childhood = through 6 years after feed.
Why Nutramigen®
ONLY eHF with Probiotic LGG®
Fast & lasting relief through early childhood1-5*†‡
Most studied§
Fewer allergies at 6 years5,6*||
WIC®¶-eligible in all 50 states
eHF = extensively hydrolyzed formula
*Published studies showing fewer incidences of urticaria, eczema, asthma, and rhinoconjunctivitis in infants with IgE-mediated cow's milk allergy through 6 years compared to hydrolyzed rice, soy, extensively hydrolyzed whey, and amino acid formulas.
†Lasting relief = reduced allergic march at 3 years and 6 years.
‡Childhood = through 6 years after feeding.
§Nutramigen® protein is clinically researched in 80+ studies.
||Hydrolyzed rice formula (HRF) vs Nutramigen® with LGG®, P < 0.001; soy formula vs Nutramigen® with LGG®, P < 0.001; extensively hydrolyzed whey formula (EHWF) vs Nutramigen® with LGG®, P < 0.001; amino acid formula (AAF) vs Nutramigen® with LGG®, P < 0.001. P < 0.0123 for overall statistical analysis including Nutramigen® with LGG®, HRF, soy formula, EHWF, and AAF.
¶WIC® is a registered trademark of the United States Department of Agriculture (USDA) for the Special Supplemental Nutrition Program for Women, Infants, and Children. No endorsement of any brand or product by the USDA is implied or intended.
How it works
Nutramigen® is the only formula with a unique peptide profile and Probiotic LGG®.
Extensively hydrolyzed casein peptides reduce allergen exposure and may act as regulators of the immune system response.7-9
Probiotic LGG® supports the growth of beneficial gut bacteria, improves gut barrier integrity, and helps reduce allergic inflammation.10-13
Clinical studies
Nutramigen® significantly improved GI and skin symptoms in infants with suspected CMPA by the next physician visit.4
STUDY DESIGN (Wilsey et al. 2023): Prospective cohort analysis of de-identified patient data collected by HCPs who analyzed the clinical profile of infants displaying symptoms consistent with CMPA or diagnosed with CMPA. Inclusion criteria included patients less than 6 months of age prescribed extensively hydrolyzed formula LGG® at the enrollment visit (Visit 1) whose HCPs provided symptom data at Visit 1 and the next visit (Visit 2) at 3 to 6 weeks (n = 202).
The percent improvement is calculated by determining the percent difference in the incidence of total presented symptoms (at different severity levels: low, moderate, and severe) between Visit 1 and Visit 2.
~50% less risk of asthma, eczema, and rhinitis through early childhood5,6†‡
STUDY DESIGN (Nocerino et al. 2025): This study expanded on a previous prospective cohort study conducted by the same research team (Nocerino et al. 2021) on non-breastfed infants with suspected IgE-mediated CMPA by extending the total period of observation to 72 months. Of the 365 children in the initial 36-month study, 313 were available in the 72-month follow-up. The main outcome was the impact of each formula on the cumulative incidence of allergic manifestations over the 72-month observation period. The incidence was significantly lower with Nutramigen® with LGG® vs each of the other formulas (P < 0.001 for all comparisons). The other formulas included (1) hydrolyzed rice formula, (2) soy formula, (3) amino acid formula, and (4) extensively hydrolyzed whey formula.
CMPA = cow's milk protein allergy; IgE = immunoglobulin E
*Number of patients who presented with the reported issue at the first visit and were assessed at the second visit.
†Published studies showing fewer incidences of urticaria, eczema, asthma, and rhinoconjunctivitis in infants with IgE-mediated cow's milk allergy through 6 years compared to hydrolyzed rice, soy, extensively hydrolyzed whey, and amino acid formulas.
‡Hydrolyzed rice formula (HRF) vs Nutramigen® with LGG®, P < 0.001; soy formula vs Nutramigen® with LGG®, P < 0.001; extensively hydrolyzed whey formula (EHWF) vs Nutramigen® with LGG®, P < 0.001; amino acid formula (AAF) vs Nutramigen® with LGG®, P < 0.001. P < 0.0123 for overall statistical analysis including Nutramigen® with LGG®, HRF, soy formula, EHWF, and AAF.
Zero blood in stools
Infants given Nutramigen® with Probiotic LGG® had no blood in their stools at 4 weeks.2*
Less eczema
Reduced eczema severity from moderate eczema to mild eczema in just 4 weeks.3*
Less crying
- Starts to reduce excessive crying† in less than 24 hours1
- A significant reduction in excessive crying was observed within 48 hours1‡
*Reduced eczema (SCORAD index) and blood in stools within 1 month compared to Nutramigen® without LGG®.
†Due to cow's milk protein allergy (CMPA). Studied before the addition of DHA, ARA, or LGG®.
‡Reduced crying in ~90% of infants within 48 hours when managing colic due to cow's milk allergy. Studied before the addition of DHA, ARA, or LGG®.
Patient support
Mead Johnson Nutrition offers a range of savings and assistance programs to support parents when they need it most.
Helping Hands™ Sample Assistance
Free one-time shipment of Nutramigen®* per child, per household.
Helping Hands™ Reimbursement Support
Insurance assistance available for select Mead Johnson Nutrition products when prescribed.
WIC®†
WIC® provides infant formula vouchers and food vouchers to eligible families and for children up to age 5 found to be at nutritional risk. WIC® contracts do not dictate your recommendation.
SNAP‡
SNAP provides a monthly dollar amount on a preloaded card to families who qualify. Participants can use SNAP benefits to purchase food and any baby formula, including Enfamil® products.
*Per child, per household; other Enfamil® formulas also eligible.
†WIC® is a registered trademark of the United States Department of Agriculture (USDA) for the Special Supplemental Nutrition Program for Women, Infants, and Children. No endorsement of any brand or product by the USDA is implied or intended.
‡SNAP, Supplemental Nutrition Assistance Program, is a federal government-supported program that offers nutrition assistance to qualifying low-income individuals.
Explore the entire Nutramigen® portfolio
Nutramigen® Ready-to-Feed does not have Probiotic LGG®.