Baby sitting behind Nutramigen hypoallergenic formula can surrounded by wooden blocks spelling out common allergens like milk, eggs, and peanuts

Disrupt allergies today and tomorrow with Nutramigen®

Faster cow's milk allergy relief today.*†‡ Fewer allergy problems, like asthma and eczema, tomorrow.§

*Reduced crying in ~90% of infants within 48 hours when managing colic due to cow's milk allergy. Studied before the addition of DHA, ARA, or LGG®.

†Reduced eczema (SCORAD index) and blood in stools within 1 month compared to Nutramigen® without LGG®.

‡Helps more babies overcome cow's milk allergy and return to consuming regular milk proteins in as fast as 6 months of feeding compared to Nutramigen® without LGG®.

§Published study showing fewer incidences of asthma, rhinoconjunctivitis, urticaria, and eczema at 3 years compared to Nutramigen® without LGG®. Feeding began at 4 months of age or older in the study.

Why Nutramigen®

ONLY eHF with Probiotic LGG®

Fast relief*†‡

Most studied

Fewer future allergic manifestations‖

WIC®¶-eligible in all 50 states

eHF = extensively hydrolyzed formula

*Reduced crying in ~90% of infants within 48 hours when managing colic due to cow's milk allergy. Studied before the addition of DHA, ARA, or LGG®.

†Reduced eczema (SCORAD index) and blood in stools within 1 month compared to Nutramigen® without LGG®.

‡Helps more babies overcome cow's milk allergy and return to consuming regular milk proteins in as fast as 6 months of feeding compared to Nutramigen® without LGG®.

§Nutramigen® protein is clinically researched in 80+ studies.

‖Published study showing fewer incidences of asthma, rhinoconjunctivitis, urticaria, and eczema at 3 years compared to Nutramigen® without LGG®. Feeding began at 4 months of age or older in the study.

¶WIC® is a registered trademark of the United States Department of Agriculture (USDA) for the Special Supplemental Nutrition Program for Women, Infants, and Children. No endorsement of any brand or product by the USDA is implied or intended.

How it works

Nutramigen® is the only formula with a unique peptide profile and Probiotic LGG®.

Extensively hydrolyzed casein peptides reduce allergen exposure and may act as regulators of the immune system response.^1-3

Probiotic LGG® supports the growth of beneficial gut bacteria, improves gut barrier integrity, and helps reduce allergic inflammation.^4-7

Clinical studies

Nutramigen^® significantly improved GI and skin symptoms in infants with suspected CMPA by the next physician visit.⁸

Bar chart showing GI issues improvement between two visits: bloody/mucoid stool decreased 92%, diarrhea decreased 84%, and vomiting decreased 77%.

Bar chart showing skin issue improvements from Visit 1 to Visit 2: Rash/Eczema 74% improvement, Erythema 88% improvement, Itching 79% improvement in infants.

STUDY DESIGN (Wisley et al. 2023): Prospective cohort analysis of de-identified patient data collected by HCPs who analyzed the clinical profile of infants displaying symptoms consistent with CMPA or diagnosed with CMPA. Inclusion criteria included patients less than 6 months of age prescribed extensively hydrolyzed formula LGG® at the enrollment visit (Visit 1) whose HCPs provided symptom data at Visit 1 and the next visit (Visit 2) at 3 to 6 weeks (n = 202).

The percent improvement is calculated by determining the percent difference in the incidence of total presented symptoms (at different severity levels: low, moderate, and severe) between Visit 1 and Visit 2.

See the study

Only Nutramigen^® with Probiotic LGG® is shown to significantly reduce future allergic manifestations.^9†‡

STUDY DESIGN (Nocerino et al. 2025): This study expanded on a previous prospective cohort study conducted by the same research team (Nocerino et al. 2021) on non-breastfed infants with suspected IgE-mediated CMPA by extending the total period of observation to 72 months. Of the 365 children in the initial 36-month study, 313 were available in the 72-month follow-up. The main outcome was the impact of each formula on the cumulative incidence of allergic manifestations over the 72-month observation period. The incidence was significantly lower with Nutramigen® with LGG® vs each of the other formulas (P < 0.001 for all comparisons). The other formulas included (1) hydrolyzed rice formula, (2) soy formula, (3) amino acid formula, and (4) extensively hydrolyzed whey formula.

See the study

CMPA = cow's milk protein allergy; IgE = immunoglobulin E

*Number of patients who presented with the reported issue at the first visit and were assessed at the second visit.

†Allergic manifestations included urticaria, eczema, asthma, and rhinoconjunctivitis.

‡Hydrolyzed rice formula (HRF) vs Nutramigen® with LGG®, P < 0.001; soy formula vs Nutramigen® with LGG®, P < 0.001; extensively hydrolyzed whey formula (EHWF) vs Nutramigen® with LGG®, P < 0.001; amino acid formula (AAF) vs Nutramigen® with LGG®, P < 0.001. P < 0.0123 for overall statistical analysis including Nutramigen® with LGG®, HRF, soy formula, EHWF, and AAF.

More data on fast CMPA relief

Zero blood in stools

Infants given Nutramigen^® with Probiotic LGG^® had no blood in their stools at 4 weeks.^10*

Less eczema

Reduced eczema severity from moderate eczema to mild eczema in just 4 weeks.^11*

Less crying

Starts to reduce excessive crying† in less than 24 hours¹²
A significant reduction in excessive crying was observed within 48 hours^12‡

*Reduced eczema (SCORAD index) and blood in stools within 1 month compared to Nutramigen® without LGG®.

†Due to cow's milk protein allergy (CMPA). Studied before the addition of DHA, ARA, or LGG®.

‡Reduced crying in ~90% of infants within 48 hours when managing colic due to cow's milk allergy. Studied before the addition of DHA, ARA, or LGG®.

Ingredient transparency

Explore the function behind the ingredients in Nutramigen^®.

Learn more

Patient savings & support programs

Mead Johnson Nutrition offers a range of savings and assistance programs to support parents when they need it most.

Helping Hands™ Sample Assistance:
FREE one-time shipment of Nutramigen®* per child, per household

Helping Hands™ Reimbursement Support:
Available for select Mead Johnson Nutrition products when prescribed

Orange hexagonal badge with white text reading "WIC* Eligible"

Nutramigen® is available through WIC®† in all 50 states. WIC® program contracts
do not dictate your recommendation

Red badge with white checkmark and "SNAP BENEFITS ACCEPTED" text indicating store accepts SNAP food assistance payments

Available through SNAP‡

Learn More

*Per child, per household; other Enfamil® formulas also eligible.

†WIC® is a registered trademark of the United States Department of Agriculture (USDA) for the Special Supplemental Nutrition Program for Women, Infants, and Children. No endorsement of any brand or product by the USDA is implied or intended.

‡SNAP, Supplemental Nutrition Assistance Program, is a federal government-supported program that offers nutrition assistance to qualifying low-income individuals.

Learn more about Nutramigen®