
Enfamil® Gentlease®
Enfamil Gentlease is a 20 Cal/fl oz, milk-based infant formula designed to reduce fussiness, gas and crying.1 It has an easy-to-digest milk protein blend patterned after breast milk (whey and casein in a 60:40 ratio)* that has been partially broken down. The formula is nutritionally balanced and has docosahexaenoic acid (DHA) and arachidonic acid (ARA), nutrients also found in breast milk that promote brain and eye development.
Enfamil Gentlease is designed to reduce fussiness, gas and crying in 24 hours1
A special blend of easy-to-digest proteins that have been partially broken down
- Has ~20% of lactose* as a source of carbohydrates; infants with transient lactase deficiency generally can tolerate formulas with some lactose
Clinically proven† DHA at 0.32% of total fatty acids, the same as the worldwide breast milk average‡2
DHA is:
- Clinically proven†to support mental, visual and immune system development3–6
- Clinically shown to improve long-term cognitive outcomes through 5 years of age†7
- Shown to improve respiratory health through the first 3 years of life when infants were fed through 12 months†3
Additional product features:
- No artificial flavors, sweeteners or colors
- Kosher Dairy (OU-D), Halal
*Of a routine formula.
†Studies compared infants fed Enfamil® with DHA and ARA vs. discontinued Enfamil without DHA and ARA; studied before the addition of prebiotics.
‡Average amount of DHA in worldwide breast milk is 0.32% ± 0.22% (mean ± standard deviation of total fatty acids) based on an analysis of 65 studies of 2,474 women.2
DIGESTION DISCOMFORT AND THE IMMATURE GUT
In otherwise healthy infants, digestive discomfort may occur because infants have an immature gut. This video discusses the developing infant digestive system and how formula with partially hydrolyzed protein and reduced lactose can help.
HELP PARENTS CONCERNED ABOUT FUSSINESS, GAS, OR CRYING
Frequently asked questions about feeding issues and Enfamil Gentlease to share with parents.
ENFAMIL GENTLEASE REDUCED FUSSINESS, GAS AND CRYING WITHIN 24 HOURS
Contact Mead Johnson
*Women, Infant and Children program is a registered trademark of the United States Department of Agriculture (USDA) for the Women, Infants, & Children Program. No endorsement of any brand or product by the USDA is implied or intended.
Enfamil Gentlease is designed to provide the sole source of nutrition for infants up to age 6 months and provide a major source of nutrition for the remainder of the first year.
*Comparison to whey-to-casein ratio of typical mature breast milk (15 days to 6 months after birth) prior to hydrolysis.
Ingredients: Powder: Corn syrup solids, partially hydrolyzed nonfat milk and whey protein concentrate solids (soy), vegetable oil (palm olein, soy, coconut and high oleic sunflower oils) and less than 2%: Mortierella alpina oil*, Schizochytrium sp. oil†, vitamin A palmitate, vitamin D3, vitamin E acetate, vitamin K1, thiamin hydrochloride, riboflavin, vitamin B6 hydrochloride, vitamin B12, niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid, choline chloride, inositol, calcium carbonate, calcium phosphate, magnesium phosphate, ferrous sulfate, zinc sulfate, manganese sulfate, cupric sulfate, sodium selenite, sodium citrate, potassium chloride, potassium iodide, taurine, L-carnitine.
*A source of arachidonic acid (ARA).
†A source of docosahexaenoic acid (DHA).
POTENTIAL ALLERGENS
Enfamil Gentlease contains milk and soy.
Ingredient Transparency
Explore the function behind our ingredients.
| (Normal Dilution) | Per 100 Calories (5 fl oz) | Per 100 mL Powder | Per 100 grams Powder (510 Cal) |
|---|---|---|---|
| Protein, g | 2.3 | 1.56 | 11.7 |
| Fat, g | 5.3 | 3.6 | 27 |
| Linoleic acid, mg | 780 | 540 | 4100 |
| Carbohydrate, g | 10.8 | 7.3 | 55 |
| Water, g | 133 | 90 | 2.4 |
| Vitamins/Other Nutrients | |||
| Vitamin A, IU | 300 | 200 | 1530 |
| Vitamin D, IU | 60 | 41 | 310 |
| Vitamin E, IU | 2 | 1.35 | 10.2 |
| Vitamin K, mcg | 9 | 6.1 | 46 |
| Thiamin (Vitamin B1,), mcg | 80 | 54 | 410 |
| Riboflavin (Vitamin B2,), mcg | 140 | 95 | 710 |
| Vitamin B6, mcg | 60 | 41 | 310 |
| Vitamin B12, mcg | 0.3 | 0.2 | 1.53 |
| Niacin, mcg | 1000 | 680 | 5100 |
| Folic acid (Folacin), mcg | 16 | 10.8 | 82 |
| Pantothenic acid, mcg | 500 | 340 | 2600 |
| Biotin, mcg | 3 | 2 | 15.3 |
| Vitamin C (Ascorbic acid), mg | 12 | 8.1 | 61 |
| Choline, mg | 24 | 16.2 | 122 |
| Inositol, mg | 6 | 4.1 | 31 |
| Minerals | |||
| Calcium, mg | 82 | 55 | 420 |
| Phosphorus, mg | 46 | 31 | 230 |
| Magnesium, mg | 8 | 5.4 | 41 |
| Iron, mg | 1.8 | 1.22 | 9.2 |
| Zinc, mg | 1 | 0.68 | 5.1 |
| Manganese, mcg | 15 | 10.1 | 77 |
| Copper, mcg | 75 | 51 | 380 |
| Iodine, mcg | 15 | 10.1 | 77 |
| Selenium, mcg | 2.8 | 1.89 | 14.3 |
| Sodium, mg | 40 | 24 | 184 |
| Potassium, mg | 108 | 73 | 550 |
| Chloride, mg | 63 | 43 | 320 |
Product nutrient values and ingredients are subject to change. Please see product label for current information.
| Nutrient Density | 20 Calories/fl oz |
|---|---|
| Protein (% Calories) | 9 |
| Whey:Casein Ratio | 60:40 |
| Fat (% Calories) | 48 |
| Carbohydrate (% Calories) | 43 |
| Potential Renal Solute Load (mOsm/100 Calories)8 | 21 |
| Potential Renal Solute Load (mOsm/100 mL)8 | 14 |
| Osmolality (mOsm/kg water) | 230 |
| Osmolarity (mOsm/L) | 210 |
| Lactose-free | No |
AMINO ACID COMPOSITION
Essential and Nonessential Amino Acids
DILUTION INFORMATION FOR ENFAMIL GENTLEASE
Mixing instruction by the scoop
Download dilution information ↗
Mixing instructionby the quart
Download dilution information ↗
POWDER
A baby’s health depends on carefully following the instructions below. Proper hygiene, preparation, dilution, use and storage are important when preparing infant formula. Powdered infant formulas are not sterile and should NOT be fed to premature infants or infants who might have immune problems unless directed and supervised by a doctor. Discuss with parents which formula is appropriate for the baby.
Discuss with parents whether they need to use cooled, boiled water for mixing and whether they need to boil clean utensils, bottles and nipples in water before use.
WARNING: Do not use a microwave oven to warm formula. Serious burns may result.
Refer to the product label for the most accurate information.
Failure to follow these instructions could result in severe harm. Once prepared, infant formula can spoil quickly. Either feed immediately or cover and store in refrigerator at 35–40°F (2–4°C) for no longer than 24 hours. Do not use prepared formula if it is unrefrigerated for more than a total of 2 hours. Do not freeze prepared formula. After feeding begins, use formula within 1 hour or discard.
- Wash hands thoroughly with soap and water before preparing formula.
- Pour desired amount of water into bottle. Add powder.
- Cap bottle and SHAKE WELL.
Use the charts below for correct amounts of water and powder. Use scoop in tub or can to measure powder. Store DRY scoop in lid holder in tub or in can.
| To Make* | Water | Powder | Weight |
|---|---|---|---|
| 2 fl oz bottle | 2 fl oz | 1 unpacked level scoop | 8.7 g |
| 4 fl oz bottle | 4 fl oz | 2 unpacked level scoops | 17.4 g |
| 8 fl oz bottle | 8 fl oz | 4 unpacked level scoops | 34.8 g |
*Each scoop adds about 0.2 fl oz to the amount of prepared formula
ENFAMIL GENTLEASE IS AVAILABLE IN POWDER AND READY-TO-FEED LIQUID
Coding systems and reimbursement allowable rates vary by payer:
- Medicare Part B uses HCPCS (Healthcare Common Procedure Coding System) to group products
- Medicaid systems vary by state; some use HCPCS while others use NDC format code or systems of their own—contact your state provider for more information
- Private health insurance and managed care companies may use HCPCS, NDC format code or their own system—contact your provider for more information

Enfamil® Gentlease®, Powder (27.7 oz can)
Item #: 174109
Description: Powder
Unit Size: 27.7 oz can
Calories/Unit: 3960
Product Yield/Unit (fl oz): 198
Case: 4 cans per case
HCPCS Code: B4158
NDC Format Code: 00087-5121-25

Enfamil® Gentlease®, Powder (19.9 oz can)
Item #: 174108
Description: Powder
Unit Size: 19.9 oz can
Calories/Unit: 2860
Product Yield/Unit (fl oz): 143
Case: 4 cans per case
HCPCS Code: B4158
NDC Format Code: 00087-5119-78

Enfamil® Gentlease®, Powder (12.4 oz can)
Item #: 174101
Description: Powder
Unit Size: 12.4 oz can
Calories/Unit: 1780
Product Yield/Unit (fl oz): 89
Case: 6 cans per case
HCPCS Code: B4158
NDC Format Code: 00087-5100-69
- Berseth CL, Johnston WH, Stolz SI, et al. Clinical response to 2 commonly used switch formulas occurs within 1 day. Clin Pediatr(Phila). 2009;48:58-65.
- Brenna JT, Varamini B, Jensen RG, et al. Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide. Am J Clin Nutr. 2007;85:1457-1464.
- Birch EE, Khoury JC, Berseth CL, et al. The impact of early nutrition on incidence of allergic manifestations and common respiratory illnesses in children. J Pediatr. 2010;156:902-906.
- Birch EE, Hoffman DR, Uauy R, et al. Visual acuity and the essentiality of docosahexaenoic acid and arachidonic acid in the diet of term infants. Pediatr Res. 1998;44:201-209.
- Birch EE, Garfield S, Hoffman DR, et al. A randomized controlled trial of early dietary supply of long-chain polyunsaturated fatty acids and mental development in term infants. Dev Med Child Neurol. 2000;42:174-181.
- Morale SE, Hoffman DR, Castaneda YS, et al. Duration of long-chain polyunsaturated fatty acids availability in the diet and visual acuity. Early Hum Dev. 2005;81:197-203.
- Colombo J, Carlson SE, Cheatham CL, et al. Long-term effects of LCPUFA supplementation on childhood cognitive outcomes. Am J Clin Nutr. 2013;98:403-412.
- Fomon SJ, Ziegler EE. Renal solute load and potential renal solute load in infancy. J Pediatr. 1999;134:11-14.